It is high season for people shopping for flea and tick treatments for dogs and cats. It is always for a battle for pet parents when they have to choose between Frontline Plus and Advantage II. They take the longest time to decide what to shop for flea and tick prevention treatment when the best options are in front of them.
Well, easing your dilemma about selecting between Frontline Plus or Advantage II, just read on to find out the major differences between these two products and decide finally which one to buy for your pet.
Frontline Plus for dogs is a product from Merial. It treats all life stages of fleas on the pets including its surroundings. It even kills ticks along with controlling sarcoptic mange and lice.
Contrarily, Advantage II is not capable of killing ticks. It only kills fleas, flea larvae, and controls flea allergy dermatitis and prevents chewing lice.
Merial states that Frontline Plus product kills 98- 100 % fleas. This topical solution destroys fleas and their larvae. It says that fleas are dead within 18 hours of contact with treated pet.
Bayer claims that its product Advantage II for dogs totally eradicates fleas from pets within 24 hours.
Apart from killing fleas, Advantage II destroys flea life cycle by destroying flea eggs and larvae.
Frontline Plus kills ticks within 48 hours of application. It completely eradicates ticks and prevents future tick infestation.
Advantage II does not work on ticks. The product is incapable of eradicating ticks; therefore, it is widely used only to treat fleas.
Frontline vs Advantage Comparison Chart
| Parasites | Advantage for Dogs | Frontline Plus for Dogs |
| Adult Fleas | Yes | Yes |
| Flea Eggs | No | Yes |
| Adult Larvae | Yes | Yes |
| Flea Allergy Dermatitis | Yes | Yes |
| Ticks | No | Yes |
| Heartworm | No | No |
| Roundworm | No | No |
| Hookworm | No | No |
| Whipworm | No | No |
| Tapeworm | No | No |
| Sarcoptic Mange | No | Yes |
| Earmites | No | No |
| Lice | Yes | Yes |
| Insects | No | No |
Frontline Plus is effective in killing lice and sarcoptic mange. This topical solution also eradicates different ticks such as Lone star ticks, American dog tick, deer tick, brown tick and western Blacklegged Tick.
Advantage II controls flea allergy dermatitis and kills lice.
Frontline Plus contains fipronil that kills fleas and ticks, and the other component (S) –methoprene destroys flea eggs and larvae.
Advantage II has active ingredients such as Imidacloprid and Pyriproxyfen. The first component kills fleas and the second ingredient act as insect growth regulator to kill all life stages of fleas.
How old do pets need to be for the treatment?
Frontline Plus flea and tick treatment can be given to 8 weeks and older puppies and kittens. Moreover, according to weight of dogs and cats, the dosage of Frontline Plus depends.
On the other hand, Advantage II can be given to 6 weeks and older puppies and kittens. Same as Frontline Plus, the dosage of this treatment depends on weight of dogs and cats.
What is product pack size of Frontline Plus and Advantage II?
Frontline Plus comes in single dose for 1 month supply, 3 packs for 3 month supply, 6 packs for 6 month supply and 12 packs for 12 month supply.
With a little difference in pack size, Advantage II comes as a single dose for monthly treatment, 4 packs for 4 month supply and 6 packs for 6 month supply and 12 packs for 12 month supply.
What is the Price difference between two products?
Frontline Plus costs bit higher than Advantage as it treats both fleas and ticks, whereas Advantage is slightly cheaper due to its capacity to treat fleas.
Are they harmful to humans?
Frontline Plus contains two pesticides – one for flea control and the other for the ticks. When Frontline Plus treatment is given, it is recommended to keep children away from the application for couple of days.
Advantage contains only one pesticide, so it less harmful to humans.
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